I’ve been using a few Iomega StorCenter IX4-200D’s as storage targets for vSphere 4 ESXi and have been a little disappointed at the performance. This disappointment really only comes when VMs are booting, I’m using Storage VMotion, or consolidating snapshots. For the price point, it’s still a great piece of equipment and I can honestly say that I’ve had 17+ active VMs running off the unit with no problem once the VMs are up and running. Keep in mind this is a lab implementation and those VMs weren’t under heavy utilization.
I’ll keep this post updated with anything else I come up with or that is submitted in comments.
Edited 10/23/2011 - No longer recommending use of NFS as a vSphere target on this unit.